Adherence to Healthy Lifestyle and Cardiovascular Diseases in the Chinese Population.
-04-20 11:35
作者：Lv J, Yu C, Guo Y, Bian Z, Yang L, Chen Y, Tang X, Zhang W, Qian Y, Huang Y, Wang X, Chen J, Chen Z, Qi L, Li L; China Kadoorie Biobank Collaborative Group.
机构： 北京大学医学部，北京大学环境医学研究所
期刊：《J AM COLL CARDIOL 》5月9期69卷
Adherence to a combination of healthy lifestyle factors has been related to a considerable reduction of cardiovascular risk in white populations; however, little is known whether such associations persist in nonwhite populations like the Asian population.
OBJECTIVES:
This study aimed to examine the associations of a combination of modifiable, healthy lifestyle factors with the risks of ischemic cardiovascular diseases and estimate the proportion of diseases that could potentially be prevented by adherence to these healthy lifestyle patterns.
METHODS:
This study examined the associations of 6 lifestyle factors with ischemic heart disease and ischemic stroke (IS) in the China Kadoorie Biobank of 461,211 participants 30 to 79 years of age who did not have cardiovascular diseases, cancer, or diabetes at baseline. Low-risk lifestyle factors were defined as nonsmoking status or having stopped smoking for reasons other than illness, alcohol consumption of RESULTS:
During a median of 7.2 years (3.3 million person-years) of follow-up, this study documented 3,331 incident major coronary events (MCE) and 19,348 incident ISs. In multivariable-adjusted analyses, current nonsmoking status, light to moderate alcohol consumption, high physical activity, a diet rich in vegetables and fruits and limited in red meat, and low adiposity were independently associated with reduced risks of MCE and IS. Compared with participants without any low-risk factors, the hazard ratio for participants with ≥4 low-risk factors was 0.42 (95% confidence interval: 0.34 to 0.52) for MCE and 0.61 (95% confidence interval: 0.56 to 0.66) for IS. Approximately 67.9% (95% confidence interval: 46.5% to 81.9%) of the MCE and 39.1% (95% confidence interval: 26.4% to 50.4%) of the IS cases were attributable to poor adherence to healthy lifestyle.
CONCLUSIONS:
Adherence to healthy lifestyle may substantially lower the burden of cardiovascular diseases in Chinese.
通讯机构：Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China; Peking University Institute of Environmental Medicine, Beijing, China.
上一篇：激活素受体样激酶4可减轻心肌梗死引起的心肌纤维化并保存心脏功能
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学科代码：心血管病学关键词：中国人群 健康生活方式 依从性及心血管疾病 ,中国作者重要发表 爱思唯尔医学网, Elseviermed
来源：Scopus
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