Don’t lose heart; difficulties you are faced with will be overcome in the end.A. howeverB

问题补充：

Don’t lose heart; difficulties you are faced with will be overcome in the end.

A. however

B. whatever

C. what

D. How

答案：

A. however

(答案→)B. whatever

C. what

D. How

解析：考查主语从句。本句中的whatever difficulties you are faced with是一个主语从句。要注意后面的是名词difficulties ,故使用whatever来引导。However后面要接形容词或者副词来引导。“No matter+特殊疑问句”只能引导让步状语从句；“特殊疑问句+ever”既可以引导让步状语从句，也可以引导名词性从句；句意：不要失去信心，你们面对的无论什么困难最后都将被克服。故B正确。